Minggu, 23 Desember 2012

Anthrax

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Anthrax

Definition:
Anthrax

Anthrax is a serious illness caused by a spore-forming bacterium, Bacillus anthracis. Although anthrax affects mainly livestock and wild game, humans can become infected through direct or indirect contact with sick animals. Normally, anthrax isn't transmitted from person to person, but in rare cases, anthrax skin lesions may be contagious.

Most often, anthrax bacteria enter your body through a wound in your skin. You can also become infected by eating contaminated meat or inhaling the spores. Signs and symptoms, which depend on the way you're infected, can range from skin sores to nausea and vomiting or shock.
Prompt treatment with antibiotics can cure most anthrax infections contracted through the skin or contaminated meat. Inhaled anthrax is more difficult to treat and can be fatal.

Symptoms:

There are three types of anthrax, each with different signs and symptoms. In most cases, symptoms develop within seven days of exposure to the bacteria.
Cutaneous anthrax
This form of anthrax enters your body through a cut or other sore on your skin. It's by far the most common form of the disease. It's also the mildest — with appropriate treatment, cutaneous anthrax is seldom fatal. Signs and symptoms of cutaneous anthrax include:
  • A raised, itchy bump resembling an insect bite that quickly develops into a painless sore with a black center
  • Swelling in the sore and nearby lymph glands
Gastrointestinal anthrax
You contract this form of anthrax by eating undercooked meat from an infected animal. Signs and symptoms include:
  • Nausea
  • Vomiting, which is often bloody in the later stages of the disease
  • Loss of appetite
  • Fever
  • Severe, bloody diarrhea in the later stages of the disease
  • Sore throat and difficulty swallowing
  • Swollen neck
Inhalation (pulmonary) anthrax
Inhalation anthrax develops when you breathe in anthrax spores. It's the most deadly form of the disease, and even with treatment it is often fatal. Initial signs and symptoms of inhalation anthrax include:
  • Flu-like symptoms, such as sore throat, mild fever, fatigue and muscle aches, which may last a few hours or days
  • Mild chest discomfort
As the disease progresses, you may experience:
  • High fever
  • Trouble breathing
  • Shock
  • Meningitis — a potentially life-threatening inflammation of the brain and spinal cord
When to see a doctor
Many common illnesses start with symptoms that resemble the flu. Anthrax is rare in the developed world, and the chances that your sore throat and aching muscles are due to anthrax are extremely small.
If you think you may have been exposed — for example, if you work in an environment where anthrax is likely to occur — see a doctor immediately for evaluation and care. If you develop signs and symptoms of the disorder after exposure to animals or animal products in parts of the world where anthrax is common, seek prompt medical attention. Early diagnosis and treatment are crucial.


Causes:

Anthrax spores are formed by anthrax bacteria that occur naturally in soil in most parts of the world. The spores can remain dormant for years until they find their way into a host — usually wild or domestic livestock, such as sheep, cattle, horses, goats and camels. Although rare in the United States, anthrax is still common throughout the developing world, such as in Iran, Iraq, Turkey, Pakistan and sub-Saharan Africa.

Most human cases of anthrax occur as a result of exposure to infected animals or their meat or hides. In the United States, a few people have developed anthrax while making traditional African drums from the skins of infected animals.

One of the few known instances of non-animal transmission occurred in the United States in 2001 when 22 people developed anthrax after being exposed to spores sent through the mail. Five of those who were infected died.

Complications:

The most serious complication of anthrax is a fatal inflammation of the membranes and fluid covering the brain and spinal cord, leading to massive bleeding (hemorrhagic meningitis).


Treatments and drugs:

The standard treatment for anthrax is a 60-day course of an antibiotic, such as ciprofloxacin or doxycycline. Which single antibiotic or combination of antibiotics will be most effective for you depends on the type of anthrax you have, your age, overall health and other factors. Treatment is most effective when started as soon as possible.
Although some cases of anthrax respond to antibiotics, advanced inhalation anthrax may not. By the later stages of the disease, the bacteria have often produced more toxins than drugs can eliminate.

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